09:00
L06 - Design and synthesis of aminosteroids and steroidal neuromuscular blocking agents
Prof. Xianming HU
WUHAN UNIVERSITY, Wuhan, Hubei, China
Hu Xianming was born in 1950, in Hubei, China. After graduation from the university in 1978, he continued to study as graduate student until 1981 when he obtained a master degree of science from the Chemistry Department of Wuhan University. He got a position of researcher at Chemistry Institute of Hubei Province in February of 1982 to January of 1985. He went back to Wuhan University again in February of 1985 and worked in the Center of Analysis Science of Wuhan University until October of 1992. He came to the Netherlands to join the Professor Kellogg's group in 1992 as a visiting scholar and a Ph.D. candidate. He got his Ph.D. degree in Groningen University of the Netherlands in 1995. Prof. Hu Xianming was the dean of pharmacy college in Wuhan university (from May of 2001 to June of 2010).
His research work covers a wide range of organic chemistry and medicinal chemistry. he has published over 100 papers and declared 14 chinese patents.
Recent research interests at his laboratory focus on:
(1) Medicinal chemistry including natural products and traditional medicine.
(2) Biomaterials and drug delivery system.
phone number:0862768759887(O); fax:0862768759100
E-mail: xmhu@whu.edu.cn
09:50
OC04 - Nouvelle voie de synthèse de derivés furo[3,2-b]pyridiniques à activité mélatoninergique
Ms Audrey COUHERT
ICOA, Orléans, France
10:05
Pause-café et communications par affiche, session 3
10:55
L07 - L’oligomérisation des récepteurs couplés aux protéines G et complexes protéiques associés: de nouvelles opportunités pour le drug design
Dr Ralf JOCKERS
UNIVERSITÉ PARIS DESCARTES, Paris, France
Ralf Jockers is researcher at INSERM, currently working at the Institut Cochin (Paris). After studying biology and biochemistry at the University of Cologne (Germany), he performed his doctoral thesis in Braunschweig (Germany) on the "Development of biosensors for herbicides on the basis of the photosystem of phototrophic bacteria”. In 1993, he received a scholarship from the European community to perform his post-doctoral training with Prof. Dr. A. D. Strosberg (Paris). It was here that he became interested in G protein-coupled receptors (GPCRs). Since 2002 he runs his own research team that studies the role of GPCRs, in the development of obesity, diabetes and mental disorders. He is co-author of >100 research articles and gave >80 invited conferences, is a member of the Faculty of 1000 (Molecular Pharmacology section) and Editor-in-Chief of « Frontiers in Cellular Endocrinology ».
11:45
OC05 - Novel development in coumarins as FXIIa inhibitors: Improvement of solubility
Mrs Charlotte BOUCKAERT
UNAMUR, Namur, Belgium
12:00
OC06 - Synthesis and evaluation of harmine derivatives as new cytostatic compounds on cancerous cells
Mrs Celine MEINGUET
UNAMUR, Namur, Belgium
12:15
13:45
L08 - Structure, function and inhibition of human protein kinase CK2
Prof. Marc LE BORGNE
UNIVERSITÉ CLAUDE BERNARD LYON 1, Lyon, France
Après des Etudes de Pharmacie (1992) et un DEA de « Chimie fine » (1993), l’étudiant Marc LE BORGNE a effectué une Thèse d’Université à Nantes dans le Laboratoire de Pharmacochimie dirigé par le Pr. Guillaume Le Baut, sur une thématique principalement focalisée autour de la conception et la synthèse d’inhibiteurs non stéroïdiens de l’aromatase. En 1999, il a ensuite intégré l’Université Atlantique de Nantes comme Maître de Conférences à la Faculté de Pharmacie. Ses thématiques de recherche ont évolué vers de nouvelles cibles thérapeutiques comme la lanostérol 14-déméthylase et le couple de kinases PI3K/Akt.
En 2008, il a poursuivi sa carrière d’Enseignant-Chercheur à l’Université Claude Bernard Lyon 1 en tant que Professeur de Chimie Thérapeutique. Depuis le 1er janvier 2011, il dirige l’Equipe de Recherche « EA 4446 Biomolécules Cancer et Chimiorésistances ». De nouvelles cibles thérapeutiques sont en cours de développement comme la pompe d’efflux ABCG2 et la protéine kinase CK2.
14:35
L09 - The dynamics of protein-DNA recognition in the telomere
Dr Charles LAUGHTON
UNIVERSITY PARK NOTTINGHAM, Nottingham, United Kingdom
Charlie Laughton is Associate Professor and Reader in Molecular Recognition, in the School of Pharmacy, University of Nottingham. Charlie studied for his DPhil in synthetic organic chemistry under George Fleet at Oxford before spending three years as a postdoc with the Cancer Chemotherapy Research Group at Aston University (Birmingham) working with Malcolm Stevens, Andy Gescher, and John Hickman. He then moved to the Institute of Cancer Research in London for seven years, working with Steven Neidle, before taking up a position in the School of Pharmacy at Nottingham. Charlie's main interests are in the study of biomolecular recognition and function, and the translation of these studies into drug discovery and development projects.
15:25
Pause-café et communications par affiche, session 4
16:15
OC07 - Antiplasmodial SARs in 2-trichloromethylazaheterocyclic series
Dr Nicolas PRIMAS
FACULTÉ DE PHARMACIE DE MARSEILLE, Marseille, France
16:30
OC08 - Discovery of highly potent, selective and safe reversers of BCRP-mediated multidrug resistance
Ms Florine LECERF-SCHMIDT
UJF, Grenoble, France
16:45
OC09 - Metalloprotease inhibitors targeting: new strategy for chondrosarcoma treatment
Dr Magali VIVIER
UMR 990 INSERM, Clermont-Ferrand, France
17:00
OC10 - Design and synthesis of 2-indolyl-thieno[2.3-d]pyrimidinones as potential inhibitors of VEGFR2
Dr Stéphanie HESSE
UNIVERSITÉ DE LORRAINE, Metz, France
17:15
OC11 - 1,4-dihydropyridines as antiproliferative and multidrug resistance reversal agents
Mr Conor O'SHEA
TRINITY COLLEGE DUBLIN, Dublin, Ireland
17:30
OC12 - Développement de nanoparticules de type PLGA de petite taille contenant du Paclitaxel: Etude de l’activité antiproliférative et des interactions moléculaires
dans un modèle de cellules cancéreuses prostatiques humaines
Dr Christophe FURMAN
UNIVERSITY OF LILLE, FACULTY OF PHARMACY, Lille, France
17:45
19:30