Registration

Welcome and Opening

The Fascinating World of Medicinal Chemistry and Drug Discovery

OC01 - A Novel Hydantoin-Based Series of Dpre1 Inhibitors in M.Tuberculosis: Hit-to-Lead Optimization and Biological Profiling

OC02 - Target Elucidation of Novel Trypanosomatid Inhibitors
Winner of the young medicinal chemist meeting in the United Kingdom

OC03 - Design, Synthesis and Biological Evaluation of New Artemisinin Hybrid Molecules
Winner of the young medicinal chemist meeting in Greece

OC04 - Development of Non-Covalent In Vivo Active Butyrylcholinesterase Inhibitors
Winner of the young medicinal chemist meeting in Slovenia

Flash Poster Presentations

FP01- 3rd-Generation Analogs of Meiogynine A, New Multiple Inhibitors of Anti-Apoptotic Proteins of Bcl-2 Family

FP02 - Slow But Steady Wins The Race: Influenza A M2/V27a Resistance Mechanism

FP03 - New Vistas in Lithium Halocarbenoids Mediated Homologations

FP04 - Synthesis of Hydroxy Lactones by Selenium-Mediated Oxidation/Cyclization of Alkenoic Acids Under Eco-Flow Conditions

FP05 - Metabolite Identification and Total Synthesis of Metabolically Stabilized Analogs of The Natural Product Pironetin

FP06 - New Allosteric Modulator of The Cb2 Receptor and its Potential Application in Neuropathic Pain

FP08 - Small Molecules for In Situ Cell Manipulation as A Regenerative Medicine Strategy

FP09 - Synthesis and Biological Activity of Novel Atypical Dopamine Re-Uptake Inhibitors for The Treatment of Dementia

FP10 - A Multifaceted α-Enaminone: Adaptable Building Block for Synthesis of Heterocyclic Scaffolds Through Conceptually Distinct 1,2-, 1,3-, 1,4- and C-O Bond Forming Annulations

FP11 - Investigating The Impact of Covalency on Protac-Mediated Degradation of Btk

FP12 - Protein Modelling and Virtual Screening to Identify New Inhibitors Targeting The Lsrk Kinase

FP13 - Towards A Pharmacological Neuroregenerative Therapy

FP14 - Novel α-Amino Diarylphosphonates as Inhibitors of E.Coli Clpp Protease

FP15 - Design of Novel Imidazopyridazines as Strong Haspin Inhibitors

FP16 - Design of New Ezh2 Inhibitors Using Pharmacophoric Models

FP17 - Development of Novel Prodrug Designs Activated by Nitroreductase

FP18 - Synthesis of Heterocycle-Bridged Peptidic Macrocycles Via 1,3-Diyne Transformations

FP19 - Controlling The Redox Transcription Factor Regulator Pirin: Rational Design, Activity Cliffs and Metal-Dependency

FP20 - Indolactam V and Derivatives: Potential Tools for Contact-Independant iPSC Culture

YMCS Poster presentation session 1 & Networking drink

End of the day

OC05 - Identification of potent inhibitors of the anti-infective target DXS using ligand-based virtual screening
Winner of the young medicinal chemist meeting in Germany (DPhG)

OC06 - In Situ Ugi Four-Component Reaction for the Protein-Templated Identification of Inhibitors of Endothiapepsin
Winner of the young medicinal chemist meeting in the Netherlands

OC07 - Design and Synthesis of Functionalized Monocyclic 3-Amino-1-Carboxymethyl-Beta-Lactams as Potential Inhibitors of Penicillin Binding Proteins of Resistant Bacteria

OC08 - Discovery and Optimization of Novel Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anticancer Agents
Winner of the young medicinal chemist meeting in Italy

OC09 - Bicyclic Constrained Peptides Targeting the EGF-EGFR Interaction
Winner of the young medicinal chemist meeting in Spain

Coffee Break

OC10 - Discovery and Characterization of Novel Potent F508-Del Cftr Correctors

OC11 - Facing Non-Alcoholic Steatohepatitis with Multitarget Compounds

OC12 - Development of Ligands for the Short-Chain Fatty Acid Receptor Ffa2
Winner of the young medicinal chemist meeting in Denmark

OC13 - Fluorophore One-Atom-Controlled Recognition of DNA/RNA Secondary Structure
Winner of the young medicinal chemist meeting in Croatia

Lunch & Poster session 2

OC14 - Building-up Molecular Complexity with Carbenoids: New Vistas in Homologation Chemistry
Winner of the young medicinal chemist meeting in Austria

OC15 - The Role of The Sulfonyl Group on The Conformational Preferences Of Bis-Aromatic Compounds ¬ 5-Ht6 Receptor Antagonists and Beyond
Winner of the young medicinal chemist meeting in Poland

OC16 - The Catalytic Mechanism of The Iron-dependent Sulfoxide Synthase EgtB
Winner of the young medicinal chemist meeting in Switzerland

OC17 - Modular Assembly of Reversible Multivalent Targeting Drug Conjugates
Winner of the young medicinal chemist meeting in Portugal

OC18 - Molecular Recognition and Activation Mechanisms of Bitter Taste Receptors
Winner of the young medicinal chemist meeting in Israel

Voting break

Challenging Medicinal Chemistry!

Closing and award ceremony

End of the Symposium