Topics

1) New Opportunities for Metabolic and Cardiovascular Diseases

• Exploring novel pathways for the next generation drugs
• Non-small molecule approaches in metabolic & cardiovascular disorders

2) New Breakthroughs in GPCR Structure, Function and their Impact on Drug Discovery

• Exploring GPCR heterodimers as a source of drugs
• New biophysics developments in GPCR structure and function

3) New Modalities for Challenging Targets in Drug Discovery

• Exploring novel chemical space: scaffolds inspired by nature, conjugates, alternative scaffolds, oligonucleotides, macrocyclics and constrained peptides
• Tackling biological targets from different angles: protein degradation (PROTAC)

4) Chemical Biology in Drug Discovery: Visualizing Biological Processes

• Imaging biological targets and cellular processes
• Probing biological systems with small molecules

5) Tackling Challenges in Drug Delivery and Formulation

• Making the insoluble soluble
• Novel solutions to stabilize & deliver peptides/proteins

6) Case Studies: from Target Validation to Novel Drugs (all therapeutic areas included)