16th EFMC Short Course on Medicinal Chemistry

New Opportunities in GPCR Drug Discovery

 Oegstgeest (near Leiden), The Netherlands    May 17-20, 2020

Confirmed Speakers

Case Study: Discovery of H1/H4 Dual Ligands

Prof. Iwan DE ESCH
Prof. Iwan DE ESCH
VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands

1) Computational Medicinal Chemistry approaches for Structure-Based GPCR Drug Discovery
2) Structural Cheminformatics Tools and workflows for GPCR Drug Discovery
3) Tutorial and Excercise

Dr Chris DE GRAAF
Dr Chris DE GRAAF
SOSEI HEPTARES, Cambridge, United Kingdom
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Binding and Modulating GPCRs by Inside/Outside Binding Nanobodies

Dr Raimond HEUKERS
Dr Raimond HEUKERS
QVQ, Utrecht, The Netherlands
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Discovery of Cariprazine, A Dopamine D3 Receptor Prefering Third Generation Antipsychotics

Prof. Gyorgy KESERU
Prof. Gyorgy KESERU
HUNGARIAN ACADEMY OF SCIENCES, Budapest, Hungary
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A General Introduction into GPCRdb & Hands-on with the GPCRdb

Dr Albert KOOISTRA
Dr Albert KOOISTRA
UNIVERSITY OF COPENHAGEN, København, Denmark
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1) GPCR Ligands: Molecular Recognition, Kinetics and Allosteric Modulation
2) Partial Agonism/Biased Signalling and its Therapeutical Relevance

Dr Rob LANE
Dr Rob LANE
UNIVERSITY OF NOTTINGHAM, Nottingham, United Kingdom

General Introduction to GPCRs: Pharma Relevance, Indications, Molecular Pharmacology

Prof. Rob LEURS
Prof. Rob LEURS
VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands
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System Biology Approaches to GPCR Targets

Dr Aurelien RIZK
Dr Aurelien RIZK
INTERAX BIOTECH, Villigen, Switzerland
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