17th EFMC Short Course on Medicinal Chemistry

Small Molecule Protein Degraders: A New Opportunity for Drug Design and Development

 Oegstgeest (near Leiden), The Netherlands    April 23-26, 2023

Programme


17:30

Registration

19:30

Dinner at the hotel

21:00

Get Together at the Castle Bar

08:15

Opening

08:30

Introduction to Small Molecule Degraders: PROTACS and Molecular Glues - Part 1

Prof. Alessio CIULLI
UNIVERSITY OF DUNDEE, Dundee, United Kingdom
Dr Suzanne O'CONNOR
UNIVERSITY OF DUNDEE, Dundee, United Kingdom
10:00

Coffee Break

10:30

Introduction to Small Molecule Degraders: PROTACS and Molecular Glues - Part 2

Prof. Alessio CIULLI
UNIVERSITY OF DUNDEE, Dundee, United Kingdom
Dr Suzanne O'CONNOR
UNIVERSITY OF DUNDEE, Dundee, United Kingdom
12:00

Lunch

13:30

The Ternary Complex E3-Degrader-Target: Biophysical Binding Assays and Structures - Part 1

Dr Chun-wa CHUNG
GLAXOSMITHKLINE, Stevenage, United Kingdom
15:00

Coffee Break

15:30

The Ternary Complex E3-Degrader-Target: Biophysical Binding Assays and Structures - Part 2

Dr Chun-wa CHUNG
GLAXOSMITHKLINE, Stevenage, United Kingdom
17:00

Day End

18:00

Group Walking Tour

19:30

Dinner in a Local Restaurant

08:30

Importance of Cellular Degradation Kinetics and Mechanisms for Development of Potent Therapeutic Degraders - Part 1

Dr Danette DANIELS
FOGHORN THERAPEUTICS, Cambridge, United States
10:00

Coffee Break

10:30

Importance of Cellular Degradation Kinetics and Mechanisms for Development of Potent Therapeutic Degraders - Part 2

Dr Danette DANIELS
FOGHORN THERAPEUTICS, Cambridge, United States
12:00

Lunch

13:30

Medicinal Chemistry Optimisation of Small Molecule Degraders - Part 1

Dr Andrea TESTA
AMPHISTA THERAPEUTICS, Cambridge, United Kingdom
15:00

Coffee Break

15:30

Medicinal Chemistry Optimisation of Small Molecule Degraders - Part 2

Dr Andrea TESTA
AMPHISTA THERAPEUTICS, Cambridge, United Kingdom
17:00

Day End

19:30

Dinner at the hotel

21:00

Get Together at the Castle Bar

08:30

The Current & Future Clinical Landscape of Molecular Degraders of Disease-Causing Proteins - Part 1

Dr Ingo HARTUNG
MERCK HEALTHCARE, Darmstadt, Germany
10:00

Coffee Break

10:30

The Current & Future Clinical Landscape of Molecular Degraders of Disease-Causing Proteins - Part 2

Dr Ingo HARTUNG
MERCK HEALTHCARE, Darmstadt, Germany
12:00

Wrap up and Lunch