Dr. Ing. Raimond Heukers is currently chief scientific officer of the CRO/biotech company QVQ Holding BV and postdoc in the division of Medicinal Chemistry of the VU University Amsterdam. At QVQ, he coordinates the technological expertise and progression and its contributions to national and international research projects. From a bio-chemical/medial background, Heukers obtained his PhD in cell biology at Utrecht University and gained additional expertise on antibody lead panel generation at argenx BVBA. As a postdoc, he has established the GPCR nanobody platform at the VU. He has co-authored 20+ peer reviewed papers and co-supervised multiple PhD students in national (TTW, NWO) and international projects (ITN) and contributed to successful grant applications.
Discovery of Cariprazine, A Dopamine D3 Receptor Prefering Third Generation Antipsychotics
Prof. Gyorgy KESERU
HUNGARIAN ACADEMY OF SCIENCES, Budapest, Hungary Read more
Prof. Gyorgy KESERU
György M. Keserű obtained his Ph.D. at Budapest, Hungary and joined Sanofi heading a chemistry research lab. He moved to Gedeon Richter in 1999 as the Head of Computer-aided Drug Discovery. He earned D.Sc. from the Hungarian Academy of Science in 2003 and he was invited for a research professorship at the Budapest University of Technology and Economics. Since 2007 he was appointed as the Head of Discovery Chemistry at Gedeon Richter. He contributed to the discovery of the antipsychotic Vraylar® (cariprazine) that has been approved and marketed from 2016 in US and EU. He served as a director general of the Research Centre for Natural Sciences (RCNS) at the Hungarian Academy of Sciences. From 2015 he is heading the Medicinal Chemistry Research Group at RCNS. His research interests include medicinal chemistry and drug design. He has published over 230 papers and more than 10 books and book chapters. György was awarded by the prestigious Overton and Meyer Award of the European Federation of Medicinal Chemistry. He has been elected as Fellow of the Royal Society of Chemistry and as Corresponding member of the Hungarian Academy of Sciences.
Tutorial and Excercise on GPCRdb
Dr Albert KOOISTRA
RADBOUD UMC NIJMEGEN, Nijmegen, The Netherlands
1) GPCR Ligands: Molecular Recognition, Kinetics and Allosteric Modulation
2) Partial Agonism/Biased Signalling and its Therapeutical Relevance
Dr Rob LANE
UNIVERSITY OF NOTTINGHAM, Nottingham, United Kingdom
General Introduction to GPCRs: Pharma Relevance, Indications, Molecular Pharmacology
Prof. Rob LEURS
VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands