16th EFMC Short Course on Medicinal Chemistry

New Opportunities in GPCR Drug Discovery

 Oegstgeest (near Leiden), The Netherlands    May 17-20, 2020

Confirmed Speakers

Case Study: Discovery of H1/H4 Dual Ligands

Prof. Iwan DE ESCH
VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands

1) Structural Biochemistry of GPCRs
2) GPCR Ligand Design: Cheminformatics and Modelling
3) Tutorial and Excercise

Dr Chris DE GRAAF
SOSEI HEPTARES, Cambridge, United Kingdom

Binding and Modulating GPCRs by Inside/Outside Binding Nanobodies

Dr Raimond HEUKERS
QVQ, Utrecht, The Netherlands
Read more

Discovery of Cariprazine, A Dopamine D3 Receptor Prefering Third Generation Antipsychotics

Prof. Gyorgy KESERU
HUNGARIAN ACADEMY OF SCIENCES, Budapest, Hungary
Read more

Tutorial and Excercise on GPCRdb

Dr Albert KOOISTRA
RADBOUD UMC NIJMEGEN, Nijmegen, The Netherlands

1) GPCR Ligands: Molecular Recognition, Kinetics and Allosteric Modulation
2) Partial Agonism/Biased Signalling and its Therapeutical Relevance

Dr Rob LANE
UNIVERSITY OF NOTTINGHAM, Nottingham, United Kingdom

General Introduction to GPCRs: Pharma Relevance, Indications, Molecular Pharmacology

Prof. Rob LEURS
VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands

System Biology Approaches to GPCR Targets

Dr Maria WALDHOER
INTERAX BIOTECH, Zürich, Switzerland